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In addition to a local effect, dietary Gln supplementation has been described to cause an increase of the systemic Gln concentration, which may also sustain the health and function of immune and epithelial cells 39

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35,36 Notably, ibuprofen, but not paracetamol, can directly suppress VEGF-mediated angiogenesis and vascular development in the lung through mechanisms independent of prostaglandin inhibition

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